Asti, Italy. Asti is a historic city located in the Piedmont region of Italy, famous for its wine production and medieval architecture. Stroll through the streets of the city center and admire the well-preserved towers, palaces, and churches, such as the Cathedral of Santa Maria Assunta and the Collegiata di San Secondo. Explore the wine cellars and vineyards of the surrounding Asti wine region, known for its sparkling wine, Asti Spumante. Experience the vibrant atmosphere of the annual Palio di Asti, a traditional horse race that takes place in September. Asti is a destination where history, culture, and wine converge.